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 VOLUME 15 - NUMBER 1
/ January - March 2013

 
The Changing Epidemiology of Liver Disease in HIV Patients
Vincent Soriano, Pablo Barreiro and Kenneth E. Sherman |Full Article in PDF|
Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
 
Abstract

Liver disease continues to be one of the leading causes of hospitalization and death in HIV-infected individuals. Important etiologies include both alcoholic and non-alcoholic steatohepatitis, and coinfection with hepatitis viruses B and C. While non-alcoholic fatty liver disease is increasingly diagnosed in this population, most cases of chronic hepatitis B can be well controlled with tenofovir-based regimens, and hepatitis C has entered a revolutionary era in which most patients may be cured with direct-acting antivirals. However, important gaps remain unaddressed. Hepatitis delta is a neglected disease, despite 15 million people being infected worldwide, and represents the most severe form of viral hepatitis. Hepatitis E is largely unrecognized, despite being the major cause of acute viral hepatitis worldwide and occasionally leading to chronicity in immunosuppressed individuals.

 
Key words:
Hepatitis C. HIV. Hepatitis B. Hepatitis delta. Hepatitis E. Antiviral therapy.
 
Date: 24/07/2014
ISSN: 1698-6997

 

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