HOME EDITORIAL BOARD CONTACT US SUBSCRIPTION AUTHORS INDEX AUTHORS INSTRUCTIONS SUPPLEMENTARY DATA




   
 VOLUME 15 - NUMBER 1
/ January - March 2013

 
Siglec-1: A Novel Dendritic Cell Receptor for HIV-1 Infection
Mariola López Vázquez de la Torre |Full Article in PDF|
Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
 
Abstract

Dendritic cells (DC) are essential antigen-presenting elements that regulate both the innate and acquired immune response in HIV-1 infection. This process requires HIV-1 binding to the DC surface. Initial studies suggested that DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) on immature dendritic cells (iDC) could interact with the HIV-1 gp120 envelope protein and this complex be internalized into iDC. During this process, the virus should remain intact, with iDC behaving as a “Trojan horse” for the spread of HIV-1 infection.

 
Date: 30/07/2014
ISSN: 1698-6997

 

unsubscribe 

LOGIN 
Not a member?
REGISTER 

Editor's access. 

PERMANYER PUBLICATIONS
Mallorca, 310
08037 Barcelona - Spain
Phone: +34 93 207 59 20
Fax: +34 93 457 66 42
www.permanyer.com
LINKS:
Hepatology Reviews
Hepatology Reviews
 
Cancer & Chemotherapy Reviews
Cancer & Chemotherapy
Reviews
 
trends in transplantation
Trends in Transplantation


 
© 2014 Permanyer Publications
Made & Powered by IMMA PUIG
Mallorca, 310 - 08037 Barcelona, Spain. Tel.: +34 93 207 59 20 - Fax: +34 93 457 66 42