Volume 14 - Number 3

July - September 2012



Update on Kidney Transplantation in HIV-Infected Recipients


Silas P. Norman, Mallika Kommareddi and Daniel R. Kaul |Full Article in PDF|

University of Michigan Medical Center, Ann Arbor, MI, USA


Abstract

HIV infection has historically been a contraindication to kidney transplantation. Prior to the era of potent antiretroviral therapy, the survival of HIV-infected patients was too poor to justify transplantation. In the last 15 years there has been substantial improvement in antiretroviral medications, such that HIV-positive patients are living longer and developing chronic diseases such as end-stage renal disease. The improvement in survival of HIV-positive patients has resulted in transplant centers increasingly considering infected patients appropriate for kidney transplantation. Recently, the results of the first prospective multicenter trial of kidney transplantation into HIV-positive candidates were released, showing the success and challenges of transplantation into this population. In light of the multicenter findings as well as national registry data, kidney transplantation should be considered the standard-of-care renal replacement therapy for HIV-positive end-stage renal disease patients and they should be referred and evaluated for kidney transplantation accordingly.


Key Words:

HIV. Kidney transplant. Immunosuppression. End-stage renal disease.






Contact Us

Permanyer Publications

  • Mallorca, 310 Barcelona, Spain.  08037
Phone / Fax
  • +34 93 207 59 20
  • +34 93 457 66 42
Email
  • permanyer@permanyer.com

     © 2017 Permanyer Publications  -  Legal Notice - Cookies Policy  -  ISSN 1698-6996